A visionary and poignant novel centered around former newspaperman Sam Cunningham as he prepares to die, Late City covers much of the early twentieth century, unfurling as a conversation between the dying man and a surprising God. As the two review Sam's life, from his childhood in the American South to his fledgling newspaper career in Chicago in the Roaring Twenties and the decades that follow, snippets of history are brought sharply into focus.

Sam grows up in Louisiana, with a harsh father, who he comes to resent both for his physical abuse and for what Sam eventually perceives as his flawed morality. Eager to escape and prove himself, Sam enlists in the army as a sniper while still underage. The hardness his father instilled in him helps him make it out of World War I alive, but, as he recounts these tales on his deathbed, we come to realize that it also prevents him from contending with the emotional wounds of war. Back in the US, Sam moves to Chicago to begin a career as a newspaperman. There he meets his wife and has a son, whose fate counters Sam's at almost every turn.

As he contemplates his relationships—with his parents, his brothers in arms, his wife, his editor, and most importantly, his son—Sam is amazed at what he still has left to learn about himself after all these years.