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 The Philadelphia Chromosome

Nonfiction: Life Sciences / Genetics & Genomics
Unabridged   9.75 hour(s)
Publication date: 05/14/2013

The Philadelphia Chromosome

A Mutant Gene and the Quest to Cure Cancer at the Genetic Level

Available from major retailers or BUY FROM AMAZON
Audio CD ISBN:9781622311774
Digital Download ISBN:9781622311781


Science journalist Jessica Wapner goes beyond the headlines to share the fascinating backstory on ground-breaking cancer research and the genetic science behind it.

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Product Description

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML). It is an astonishing tale that will provide victims of other cancers and their loved ones realistic hope that cures may yet be found in their lifetimes.

The Philadelphia Chromosome charts the milestones that led to present-day cancer treatment and tells the inspiring story of the dedicated men and women who, working individually and in concert, have sought to plum the mysteries of the human genome in order to conquer those deadly and most feared diseases called cancer.


“Narrator Heather Henderson conveys Wapner’s fluid prose with a calm yet dynamic delivery. . . . Recommended for all listeners.”
      —Library Journal [starred review]

“Henderson’s deep, warm voice weaves the different elements of this story—technical jargon, anecdotes, interviews, and historical details—into a coherent listening experience that extends the book’s value.”

“A refreshingly balanced view of the topic. . . . An excellent book for those who want to learn more about how medical discoveries are made and those interested in recent medical history.”
      —Library Journal

“An absorbing, complex medical detective story.”

“[Wapner’s] gracefully written history skillfully combines both the science and humanity of this fascinating search for a cure for chronic myeloid leukemia.”
      —Publishers Weekly

“The story of the Philadelphia chromosome is truly the story of modern cancer biology. . . . Jessica Wapner stitches the whole story together with tenacity, diligence (and humor). This is a wonderful, readable, and highly informative book.”
      —Siddhartha Mukherjee, Pulitzer Prize-winning author of The Emperor of all Maladies

Author Bio

JESSICA WAPNER’s science writing has appeared in Scientific American, Slate, The New York Times, New York magazine, Science, Nature Medicine, Ecologist, Scientist, and Psychology Today. Her writing on cancer has been published in patient-focused magazines CR and Cure as well as Oncology Business Review. She lives in Beacon, New York, with her husband and two young children.

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